The research work is based on observation over 651 patients with varicose disease of veins of lower extremities with С2 – С6 classes of chronic venous insufficiency treated by endovasal laser coagulation on one-day outpatient bases. Totally 1827 laser procedures were performed: GSV and LSV trunks - 646 (without preliminary crossectomy), superficial veins - 625, and incompetent perforanting veins - 538. Indications for endovasal laser coagulation and extent of intervention was defined based on the level of venous reflux, insufficiency of perforating veins and their diameters. It is observed that the process of connective tissue formation at site of coagulation takes about 1 year. The hypercoagulation disorder which is common after endovasal laser coagulation usually reverted to normal levels in weeks after procedure. Significant improvement of main stream venous blood flow was observed in patient treated by our technique as well. The complete venous obliteration of GSV and LSV trunks after endovasal laser coagulation was defined in 97,5% cases. We identified the capacities of this method for postsurgical recurrences as well as a protocol of effective combination of endovasal laser coagulation in association with echoscleroterapy and phlebectomy is defined.