WWW.DISSERS.RU


...
    !

Pages:     | 1 ||

. . 1,2,3- 02.00.03 ...

-- [ 2 ] --

T. Besson, J. Guillard, C. W. Rees, J. Chem. Soc., Perkin Trans., 2000, 563 O. A. Rakitin, C. W. Rees, O. G. Vlasova, Tetrahedron Lett., 1996, 37, 4589. J. Guillard, T. Besson, Tetrahedron, 1999, 55, 5139. H. Chabane, C. Lamazzi, V. Thiry, G. Guillaumet, T. Besson, Tetrahedron Lett., 2002, 43, 2483. T. Besson, K. Emayan, C. W. Rees, J. Chem. Soc., Chem. Commun., 1995, 1419. T. Besson, K. Emayan, C. W. Rees, J. Chem. Soc., Perkin Trans. 1, 1995, 2097. T. Besson, C. W. Rees, J. Chem. Soc., Perkin Trans. 1, 1996, 2857. P. G. Baraldi, M. G. Pavani, M. C. Nuez, P. Brigidi, B. Vitali, R. Gambari, R. Romagnoli, Bioorg. Med. Chem., 2002, 10, 449. T. Besson, J. Guillard, C. W. Rees, Tetrahedron Lett., 2000, 41, 1027. H. Lee, K. Kim, 1993, Heteroatom Chem., 4, 263. T. Besson, G. Guillaumet, C. Lamazzi, C. W. Rees, 1997, Synlett., 704. M.-K. Jeon, K. Kim, Tetrahedron Lett., 2000, 41, 1943. T. Besson, C. W. Rees, D. G. Roe, V. Thiry, J. Chem. Soc., Perkin Trans. 1, 2000, 555. C. Lamazzi, S. Lonce, B. Pfeiffer, P. Renard, G. Guillaumet, C. W. Rees, T. Besson, Bioorg. Med. Chem. Lett., 2000, 10, 2183. L. S. Konstantinova, O. A. Rakitin, C. W. Rees, S. Sivadasan, T. Torroba, Tetrahedron, 1998, 54, 9639. H.-S. Lee, Y.-G. Chang, K. Kim, J. Heterocyclic Chem., 1998, 35, 659. P. K. Mohanta, K. Kim, Tetrahedron Lett., 2002, 43, 3993. Y.-G. Chang, K. Kim, Synlett., 2002, 9, 1423. P. K. Mohanta, K. Kim, Heterocycles, 2002, 57, 1471. L. Beer, A. W. Cordes, R. C. Haddon, M. E. Itkis, R. T. Oakley, R. W. Reed, C. M. Robertson. Chem. Commun., 2002, 1872. T. M. Barclay, A. W. Cordes, R. T. Oakley, K. E. Preuss, R. W. Reed, Chem. Commun., 1998, 1039. O. A. Rakitin, C. W. Rees, O. G. Vlasova, Chem. Commun., 1996, 1274. V. Thiery, V. Beneteau, J. Guillard, C. Lamazzi, T. Besson, Pharm. Pharmacol. Commun., 1998, 4, 39. V. Thiery, T. Besson, C. W. Rees, Synthesis, 1999, 8, 1345. R. A. Cox, Bruncel, The Chemistry of the Hydrazo, Azo, and Azoxy Groups, ed. S. Patai, Interscience, New York, 1975, part 2, chapter 8, 848. Y. P. Kitaev, B. I. Buzykin and T. V. Troepolskaya, Russ. Chem, Rev., 1970, 39, 441. W. J. Kruper, A. H. Emmons, J. Org. Chem., 1991, 10, 81. 82. 83. 84. 85. 86. 87.

X. L. Jin, H. Sugihara, K. Daikai, H. Tateishi, Y. Z. Jin, H. Furuno and J. Inanaga, Tetrahedron, 2002, 58, 8321. H. Allen, O. Kennard, D. G. Watson, L. Brammer, A. G. Orpen, R. Taylor, J. Chem. Soc., Perkin Trans. 2, 1987, 81. Database of Cambridge Crystallographic Data Centre. 2003, CSD version 5.24(Jul). P. J. Steel, J. Chem. Cryst., 1996, 26, 339. I. Capuano, G. Bolz, R. Burger, V. Burkhardt. V. Huch, Liebigs Ann., 1990, 239. G. I. Nikishin, S. S. Spector, G. P. Shakhovskoi, V. G. Glukhovtsev, V. M. Zhulin, Bull. Acad. Sci. USSR Div. Chem. Sci. (Engl.Transl.), 1977, 26, 1534. G. M. Sheldrick, SHELXTL-97, Version 5.10, Bruker AXS Inc., Madison, WI-53719, USA.

88. Bruker. SMART. Bruker Molecular Analysis Research Tool. v. 5.059. Bruker AXS, Madison, Wisconsin. USA. 1998. 89. G. M. Sheldrick SHELXTL v. 5.10, Structure Determination Software Suite, Bruker AXS, Madison, Wisconsin. USA. 1998.

3. () () 5. , (). S(2)-C(6) S(2)-S(1) Cl(1)-C(2) S(1)-N(3) O(1)-N(11) C(2)-N(3) C(2)-C(6) O(4)-N(11) N(5)-N(9) N(5)-C(7) C(6)-C(7) C(7)-N(11) N(8)-C(13) N(9)-C(12) 1.726(3) 2.096(13) 1.725(3) 1.622(3) 1.227(3) 1.293(4) 1.447(4) 1.226(3) 1.290(3) 1.350(4) 1.390(4) 1.474(3) 1.146(4) 1.420(3) , (). C(6)-S(2)-S(1) N(3)-S(1)-S(2) N(3)-C(2)-C(6) N(3)-C(2)-Cl(1) C(6)-C(2)-Cl(1) C(2)-N(3)-S(1) N(9)-N(5)-C(7) C(7)-C(6)-C(2) C(7)-C(6)-S(2) C(2)-C(6)-S(2) N(5)-C(7)-C(6) N(5)-C(7)-N(11) C(6)-C(7)-N(11) N(5)-N(9)-C(12) C(17)-C(10)-C(14) O(4)-N(11)-O(1) O(4)-N(11)-C(7) O(1)-N(11)-C(7) C(15)-C(12)-C(14) C(15)-C(12)-N(9) C(14)-C(12)-N(9) N(8)-C(13)-C(14) C(10)-C(14)-C(12) C(10)-C(14)-C(13) C(12)-C(14)-C(13) C(16)-C(15)-C(12) C(15)-C(16)-C(17) C(16)-C(17)-C(10) 91.51(11) 98.30(10) 120.4(3) 116.3(2) 123.1(2) 116.2(2) 112.8(2) 128.4(3) 118.0(2) 113.5(2) 126.5(2) 110.5(2) 122.8(2) 114.0(2) 119.6(3) 125.2(2) 117.5(2) 117.2(2) 120.0(3) 124.0(2) 116.0(2) 178.6(4) 120.0(3) 119.3(3) 120.7(3) 119.3(3) 121.2(3) 120.0(3) C(10)-C(17) 1.393(4) C(10)-C(14) 1.402(4) C(12)-C(15) 1.402(4) C(12)-C(14) 1.403(4) C(13)-C(14) 1.439(4) C(15)-C(16) 1.385(4) C(16)-C(17) 1.391(4) 4. 5. X S(2) Cl(1) S(1) O(1) C(2) N(3) O(4) N(5) C(6) C(7) N(8) N(9) C(10) N(11) C(12) C(13) C(14) C(15) C(16) C(17) 1633(1) 3072(1) 1203(1) 4581(3) 2279(4) 1816(4) 1713(3) 2990(3) 2262(4) 2788(4) 1003(4) 2527(3) 2301(4) 3058(3) 2704(4) 1558(4) 2213(4) 3283(4) 3374(4) 2895(4) Y 7056(1) 7665(1) 4662(1) 11917(3) 6970(3) 5323(3) 10902(3) 10890(3) 8116(4) 9894(4) 6902(3) 10031(3) 11084(4) 10968(3) 11052(3) 8349(4) 10174(4) 12840(4) 13717(4) 12857(4) Z 8461(1) 4971(1) 7213(1) 6963(2) 6188(2) 6038(2) 6000(2) 8839(2) 7357(2) 7699(2) 11166(2) 9630(2) 12940(3) 6806(2) 10836(2) 11410(3) 11729(3) 11156(3) 12358(3) 13251(3) U(eq) 20(1) 26(1) 25(1) 31(1) 19(1) 24(1) 29(1) 19(1) 17(1) 19(1) 33(1) 18(1) 24(1) 22(1) 18(1) 23(1) 21(1) 21(1) 25(1) 25(1) 5. () () 12. , (). C(1)-N(2) C(1)-C(5) C(1)-N(5) O(1)-N(5) N(2)-N(3) O(2)-N(5) 1.3133(18) 1.370(2) 1.4409(18) 1.2152(17) 1.3214(15) 1.2101(16) , (). N(2)-C(1)-C(5) N(2)-C(1)-N(5) C(5)-C(1)-N(5) C(1)-N(2)-N(3) N(2)-N(3)-N(4) N(2)-N(3)-C(6) 110.94(13) 120.76(13) 128.30(14) 102.62(11) 114.88(12) 121.81(11) N(3)-N(4) N(3)-C(6) N(4)-C(5) N(6)-C(12) C(6)-C(7) C(6)-C(11) C(7)-C(8) C(8)-C(9) C(9)-C(10) C(10)-C(11) C(11)-C(12) 1.3396(16) 1.4198(19) 1.319(2) 1.1405(19) 1.387(2) 1.4000(19) 1.369(2) 1.379(2) 1.374(2) 1.390(2) 1.437(2) N(4)-N(3)-C(6) C(5)-N(4)-N(3) O(2)-N(5)-O(1) O(2)-N(5)-C(1) O(1)-N(5)-C(1) N(4)-C(5)-C(1) C(7)-C(6)-C(11) C(7)-C(6)-N(3) C(11)-C(6)-N(3) C(8)-C(7)-C(6) C(7)-C(8)-C(9) C(10)-C(9)-C(8) C(9)-C(10)-C(11) C(10)-C(11)-C(6) C(10)-C(11)-C(12) C(6)-C(11)-C(12) N(6)-C(12)-C(11) 123.29(11) 103.75(13) 124.63(14) 118.82(14) 116.55(14) 107.82(14) 119.74(14) 118.49(12) 121.77(12) 120.31(15) 120.68(15) 119.48(15) 121.17(15) 118.61(13) 116.35(13) 125.04(13) 171.50(15) 6. 12. X C(1) O(1) N(2) O(2) N(3) N(4) N(5) C(5) N(6) C(6) C(7) 8086(1) 8644(1) 8310(1) 9675(1) 7413(1) 6628(1) 8862(1) 7060(2) 4453(1) 7321(1) 8244(1) Y -306(1) -2287(1) 862(1) -925(1) 1403(1) 637(1) -1234(1) -460(2) 2290(1) 2698(1) 3404(1) Z 5351(2) 5636(2) 5599(2) 6966(2) 4806(1) 4082(2) 6040(2) 4427(2) 2693(2) 4701(2) 5342(2) U(eq) 51(1) 112(1) 52(1) 82(1) 47(1) 67(1) 65(1) 68(1) 79(1) 46(1) 56(1) C(8) C(9) C(10) C(11) C(12) 8183(2) 7213(2) 6298(1) 6327(1) 5312(1) 4656(1) 5235(2) 4545(1) 3272(1) 2646(1) 5284(2) 4571(2) 3918(2) 3980(2) 3288(2) 62(1) 61(1) 54(1) 47(1) 56(1) 7. 20d. X S(1) O(9) O(10) O(11) N(1) N(2) N(3) C(3) N(4) C(2) C(4) C(5) C(6) C(7) C(8) C(5) C(12) C(1A) C(2A) C(3A) C(4A) C(5A) C(6A) C(1B) 7381(1) 5138(3) 7005(4) 6143(3) 5975(4) 6103(4) 6793(3) 7035(5) 7537(4) 7097(4) 7121(4) 7686(4) 5016(4) 5875(5) 5706(6) 6873(4) 6692(4) 8213(4) 9060(4) 9590(5) 9277(6) 8439(6) 7909(5) 6961(4) Y 9505(1) 6664(2) 5849(3) 11122(2) 6643(2) 5754(3) 8709(2) 6000(3) 7032(3) 8463(3) 9772(3) 10345(3) 6659(3) 6335(3) 6317(4) 7404(3) 10230(3) 11462(3) 11896(3) 12926(3) 13550(4) 13133(4) 12087(3) 9571(3) Z 1291(1) -1327(2) -644(2) -1007(2) 744(2) 1197(2) -17(2) 1772(2) 1703(2) 716(2) -155(2) 477(2) 36(2) -678(2) -2072(2) 1049 -950(2) 547(2) -43(2) 27(3) 666(4) 1248(3) 1195(2) -1665(2) U(eq) 44(1) 56(1) 68(1) 51(1) 42(1) 58(1) 38(1) 64(1) 56(1) 37(1) 36(1) 36(1) 45(1) 48(1) 71(2) 44(1) 38(1) 38(1) 49(1) 66(1) 77(2) 69(1) 50(1) 36(1) C(2B) C(3B) C(4B) C(5B) C(6B) 8113(4) 8403(5) 7515(5) 6364(5) 6072(5) 8836(3) 8302(3) 8466(3) 9181(4) 9741(3) -1682(2) -2376(2) -3043(2) -3017(2) -2342(2) 45(1) 53(1) 57(1) 63(1) 53(1) 8. () () 20d. , (). S(1)-C(2) S(1)-C(5) O(9)-C(7) O(9)-C(8) O(10)-C(7) N(1')-C(5') N(1')-N(2') N(1')-C(6) N(2')-N(3') N(3)-C(2) N(3)-C(4) N(3')-N(4') N(4')-C(5') C(2)-C(5') C(4)-C(5) C(4)-C(12) C(5)-C(1A) C(6)-C(7) 1.725(4) 1.728(3) 1.322(5) 1.444(5) 1.181(5) 1.330(5) 1.343(4) 1.448(4) 1.295(4) 1.294(4) 1.369(4) 1.360(5) 1.319(4) 1.443(5) 1.364(5) 1.495(5) 1.463(5) 1.512(6) , (). C(2)-S(1)-C(5) C(7)-O(9)-C(8) C(5')-N(1')-N(2') C(5')-N(1')-C(6) N(2')-N(1')-C(6) N(3')-N(2')-N(1') C(2)-N(3)-C(4) N(2')-N(3')-N(4') C(5')-N(4')-N(3') N(3)-C(2)-C(5') N(3) C(2)-S(1) C(5')-C(2)-S(1) C(5)-C(4)-N(3) C(5)-C(4)-C(12) N(3)-C(4)-C(12) C(4)-C(5)-C(1A) C(4)-C(5)-S(1) C(1A)-C(5)-S(1) N(1')-C(6)-C(7) O(10)-C(7)-O(9) O(10)-C(7)-C(6) O(9)-C(7)-C(6) N(4')-C(5')-(N1') N(4')-C(5')-C(2) 89.19(18) 116.6(4) 108.7(3) 130.1(3) 121.2(3) 105.9(3) 110.5(3) 111.4(3) 104.9(3) 124.0(3) 115.2(3) 120.8(3) 116.3(3) 125.6(3) 117.8(3) 131.6(3) 108.8(3) 119.5(3) 110.4(3) 126.8(4) 124.2(4) 108.9(4) 109.1(3) 125.3(4) O(11)-C(12) 1.212(4) C(12)-C(1B) 1.485(5) C(1A)-C(6A) 1.376(5) C(1A)-C(2A) 1.386(5) C(2A)-C(3A) 1.364(6) C(3A)-C(4A) 1.367(6) C(4A)-C5(A) 1.364(6) C(5A)-C(6A) 1.381(6) C(1B)-C(2B) 1.380(5) C(1B)-C(6B) 1.386(5) C(2B)-C(3B) 1.381(5) C(3B)-C(4B) 1.370(5) C(4B)-C(5B) 1.365(6) C(5B)-C(6B) 1.368(5) N(1')-C(5')-C(2) O(11)-C(12)-C(4) C(1B)-C(12)-C(4) C(6A)-C(1A)-C(5) C(2A)-C(1A)-C(5) 125.6(3) 120.4(3) 118.6(3) 121.3(4) 119.5(4) O(11)-C(12)-C(1B) 120.9(3) C(6A)-C(1A)-C(2A) 119.2(4) C(3A)-C(2A)-C(1A) 120.0(4) C(2A)-C(3A)-C(4A) 120.9(5) C(5A)-C(4A)-C(3A) 119.6(5) C(4A)-C(5A)-C(6A) 120.4(5) C(1A)-C(6A)-C(5A) 119.9(4) C(2B)-C(1B)-C(6B) 119.5(4) C(2B)-C(1B)-C(12) 121.6(3) C(6B)-C(1B)-C(12) 118.8(4) C(1B)-C(2B)-C(3B) 120.0(4) C(4B)-C(3B)-C(2B) 120.3(4) C(5B)-C(4B)-C(3B) 119.2(4) C(4B)-C(5B)-C(6B) 121.7(4) C(5B)-C(6B)-C(1B) 119.2(4)

Pages:     | 1 ||



2011 www.dissers.ru -

, .
, , , , 1-2 .